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Endpoints included body weight, fat mass (NMR spectroscopy), glucose tolerance, and adipose-tissue NNMT enzymatic activity [1]

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These sORF produce bioactive peptides, collectively known as mitochondrial-derived peptides (MDP), which have a wide range of physiological functions and can explain how mitochondria communicate within and between cells in a specific disease environment (5)

Each mechanism attacks a different piece of the belly fat puzzle