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Oxidative damage is widely recognized as a contributor to both aging and chronic disease, making this pathway particularly relevant to dermatology and longevity research

In the cardiovascular system, senescent cells in the blood vessels promote arterial stiffness and endothelial dysfunction, increasing the risk of hypertension and atherosclerosis.25 In the brain, the buildup of senescent cells has been implicated in neurodegenerative diseases such as Alzheimers and Parkinsons, where they exacerbate neuroinflammation and neuronal loss.26 Similarly, in adipose tissue, the accumulation of senescent cells contributes to insulin resistance and the development of metabolic disorders such as type 2 diabetes.27 Senescent chondrocytes promote cartilage degradation and joint inflammation

De Sanctis MT, Belcaro G, Incandela L, Cesarone MR, Griffin M, Ippolito E, Cacchio M

TrueSport Powered by the experience and values of USADA, TrueSport inspires athletes, coaches, parents, and administrators to change the culture of youth sport through cornerstone lessons of sportsmanship, character building & life skills, and clean & healthy performance, by creating leaders across communities through sport

Featuring BPC-157 peptide, BPC-157 is a peptide that helps alleviate joint pain, improve joint mobility, and boost recovery from injuries