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1,4,6 In addition, a number of integrative interventions have been identified as having protective effects on brain function

However, most cancers give rise to upregulated anti-ferroptotic defense systems in order to escape ferroptosis

High dose aspirin is uricosuric, while low dose causes urate retention (Roch-Ramel et al., 1997

J Cell Mol Med (2017) 21:64857

Under physiological conditions, a healthy gut microbiota and an intact intestinal barrier are critical for establishing immune tolerance ( The tumor immune microenvironment (TIME), a dynamic ecosystem of cancer cells, stromal cells, ECM, and diverse immune cells, profoundly shapes tumor progression and therapeutic responses ( A pivotal mechanism linking gut dysbiosis to pro-tumorigenic inflammation is the translocation of microbial components, most notably lipopolysaccharide (LPS), across a compromised intestinal barrier ( Beyond TLR-dependent microbial sensing, the NF-B pathway serves as a critical signaling hub that integrates diverse pro-tumorigenic stimuli within the TIME