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10.1093/nar/gkab1028 47 GilmourN.KernP

The systemic impact of age-related AT dysfunction extends beyond local effects, contributing to widespread metabolic dysfunction and chronic low-grade inflammation (401)

Increased formation of oxidative DNA damage, 8-hydroxy-2-deoxyguanosine, in human breast cancer tissue and its relationship to GSTP1 and COMT genotypes

Additionally, in vitro models derived from different species, such as rats and rabbits, complicate the extrapolation of results to human clinical conditions due to interspecies differences