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The problem with glutathione is that it is functionally difficult to physiologically increase through supplementation

In principle, using inhibitory chelators would be a great strategy to prevent OH production

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Importantly, the cells response to injury can also vary in accordance with the level of stress (low versus high) and the length of exposure (acute versus chronic), such that young healthy cells may counter acute stress more formidably that aged cells, specifically effecting cellular processes including autophagy, phagocytosis, proteosomal degradation, toxic clearance and metabolism, among others