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Some microRNAs including miR-21, mir-200, and let-7 were found to be dysregulated in uterine fibroids and associated with the growth and the accumulation of extracellular matrix of uterine fibroids via aberrant expression of the target genes

However, both isoforms have demonstrated their effectiveness in ovarian function and metabolism in patients with PCOS

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Pharmacopsychiatry 34 : S98S102

The outcome of antipsychotic discontinuation would trigger a new treatment exposure period of no antipsychotic use in our study (i.e., 60-day period without any antipsychotic medication after the last antipsychotic prescriptions days supply was exhausted) and, indeed, these periods of no antipsychotic use were associated with a 11% to 32% higher risk of psychiatric hospitalization compared to periods with use of oral risperidone or other LAI reference groups