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10.1038/s41440-022-01111-y Summary Keywords SIRT1, cardiovascular diseases, endothelial dysfunction, oxidative stress, therapeutic targets Citation Dinislam K, Khoso MA, Kataev VA, Meshcheryakova S, Liu H, Liu L, Guo M, Wang S, Lou H, Zhang Y and Liu X (2026) SIRT1: The first key to unlocking the mystery of cardiovascular diseases