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As the name suggests, this is a form of cell death caused by copper, in which copper ions directly bind to protein lipoylation components in the tricarboxylic acid circulation pathway, causing abnormal aggregation of lipoylated proteins and loss of iron-sulfur cluster protein, resulting in protein toxic stress responses and cell death (172)

Functional imaging of focal brain activation in conscious rats: impact of [ 14 C]glucose metabolite spreading and release

PARP1 serves as a master regulator of single-strand break (SSB) repair, coordinating the recruitment of downstream repair factors to sites of DNA damage (Fig

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