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Metformin interacts with AMPK through binding to subunit

In brown trout, the malondialdehyde levels and the activities of several antioxidant enzymes (eg

Figure 3A, P 0.05)

While you can supplement with a bit more than this (many supplements have 15 to 30 mg), you should not exceed the tolerable upper intake of 40 mg per day from food and supplements combined, unless supervised by a doctor