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Antidepressants have an effect on some of the neurotransmitters like norepinephrine and serotonin, which can have an effect on pain, he explains

(2) For a Part D rebatable drug with a payment amount benchmark period identified under paragraphs (c)(2) through (5) of this section, CMS will calculate the benchmark period manufacturer price as the sum of the following: (i) The product of (A) The AMP reported for the calendar quarter beginning January of the payment amount benchmark period

17 Screening should be considered in patients with risk factors, and diagnostic testing should be considered in those with suspected clinical manifestations

Consider the neuropathys severity and the patients health

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