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Additionally, SCFAs can modulate the levels of neurotransmitters and neurotrophic factors and regulate the expression of tryptophan 5-hydroxylase, the enzyme involved in the synthesis of serotonin, and tyrosine hydroxylase, the enzyme involved in the rate-limiting step in dopamine, noradrenaline, and adrenaline synthesis (18, 132, 164, 222)

Dry food is dehydrating, especially to cats that already have been diagnosed with compromised kidneys and are often already dehydrated

Daily dosing at higher amounts may require additional supply for longer cycles

However, individuals with highly sensitive or reactive skin should perform a patch test before use