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TAMs have been shown to play an important role in tumor cell genesis, development, and metastasis by regulating multiple signaling pathways

Red areas indicate increased cFOS activity and blue areas indicate decreased cFOS activity

Cathepsin B is a mediator of organelle-specific initiation of ferroptosis

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Tangs seminal mechanistic insights in acute cardio-renal syndrome revealed important contributions of venous congestion and raised intra-abdominal pressures rather than insufficient cardiac output or acute renal tubular injury, which served the physiologic basis of several novel device therapies for cardio-renal syndrome