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It is apparent from these studies that in ALS there is communication between motor neurons, astrocytes, and distinct immune cells with consequent activation at sites of neuronal injury

Russell and Brunekreef 2009)

The low hematological indices together with the observed low Fe 2+ levels suggest a microcytic anaemia in the ART-nave HIV-infected patients and support previous studies that have reported low HB, MCV and MCH in HIV treatment-nave patients compared to patients on ART [32, 33]