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10.1016/j.tcb.2022.11.007 Trends Cell Biol

doi: 10.3389/fphar.2025.1706936 Received 16 September 2025 Revised 16 December 2025 Accepted 16 December 2025 Published 09 January 2026 Volume 16 - 2025 Edited by Lucas Cezar Pinheiro, Federal University of Santa Catarina, Brazil Reviewed by Mithun Rudrapal, Vignans Foundation for Science, Technology and Research, India Linxiaoxi Ma, Fudan University, China Updates Copyright 2026 Yang, Li, Lu, Xu, Guo and He

In contrast, ROXY9 encodes a glutamate, the negative charge of which may even lead to repulsion of the ligand

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