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Description

PANoptosis: a cell death characterized by pyroptosis, apoptosis, and necroptosis

Ferroptosis suppressor protein 1 (FSP1) is a key regulator of ferroptosis, acting independently of the GPX4 pathway (66)

Toxicol Sci 91 , 365371, doi: 10.1093/toxsci/kfj165 (2006)

Cellular redox signaling, influenced by fluctuations in ROS, RNS, and antioxidant systems, governs vital functions like cell growth, programmed death, and immune responses [112]

Methods: VIR-2218-1001 is a Phase 1/2 single and multiple ascending dose study at multiple sites in Asia-Pacific (APAC) region excluding mainland China