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The absolute concentration of alpha-synuclein aggregates within the brain is far lower than that of tau or beta-amyloid, and alpha-synuclein aggregates are often co-localised with tau and beta-amyloid aggregates, which are structurally similar due to the high number of beta-pleated sheets

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On the other hand, no significant diagnostic effects were observed for Glu or GABA levels

Dre2 contains a conserved C-terminal Fe/S domain which is responsible for coordinating one 2Fe2S or one 4Fe4S cluster by cysteine residues