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16 Gpx1 may have a limited antioxidant role under normal physiological condition because Gpx1-deficient mice are healthy and fertile

GSH deficiency is associated with a number of central nervous system diseases such as Multiple Sclerosis, Autism, Bipolar disease, Alzheimers, and Parkinsons disease

89 Resistance due to Inactivation by Glutathione or GSTs Intracellular inactivation of alkylating agents has been implicated in human tumor resistance