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VEGFR2-mediated angiogenesis promotes the formation of new blood vessels, improving blood supply to tissues throughout the body

In lab and clinical research, its been observed to activate fibroblasts (the cells that produce collagen), increase glycosaminoglycan synthesis (which helps skin retain water), modulate matrix metalloproteinases (MMPs, the enzymes that break down old tissue), and act as a copper cofactor in antioxidant pathways

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Dynamic differences in oxidative stress and the regulation of metabolism with age in visceral versus subcutaneous adipose

In obese mice, chronic administration of AOD-9604 was shown to significantly increase 3- adrenergic receptor (3-AR) mRNA expression in both white and brown adipose tissue