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We note that this enhancement did not fully restore efferocytosis to the level observed in M2 macrophages, suggesting that while the PKA-HSL axis is a critical component, other M2-specific factors also contribute to maximal efferocytosis function

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Phase 2 subjects on 150mg/day averaged 13.8% weight loss with no muscle loss reported

This may be because of its calcium-blocking abilities, which help regulate the nerves and muscles instead of letting calcium activate the nerves

(Wang et al., 2018) details this: No study reported on clinical signs and symptoms of vitamin B12 deficiency (e.g