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study pinpointed the important role of mTORC1 signaling in regulating ferroptosis sensitivity in cancer cells, the contribution of mTORC1 to ferroptosis and the underlying mechanisms appear highly context-specific

Additionally, the redox couple can scavenge radicals, as two glutathione thiyl radicals react to form GSSG ( de novo synthesis, GSH degradation and metabolism, the uptake and export of GSH and GSSG and the efficient reduction of GSSG

Nat Commun 11(1):3427

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