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GHK-Cu's repair-while-you-protect story directly addresses this concern

The current study found that FPN causes oxidative brain damage, disrupting cellular membrane functions and producing excess inflammatory cytokines

Jeffery, K.J

Notably, these effective concentrations were 16,000-80,000,000 times lower than concentrations of melatonin required for comparable effects, suggesting highly potent regulatory mechanisms rather than simple antioxidant activity