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They enabled the successful delivery of the antinociceptive peptide dalargin in vivo [24]

As these substances gain mainstream popularity, the balance between innovation and safety becomes the primary focus

As a highly permeable molecule capable of crossing cellular and mitochondrial membranes, melatonin effectively scavenges reactive oxygen and nitrogen species and modulates the activity of pro-inflammatory cytokines (Srinivasan et al., 2010)

Synaptic spines The protrusions on dendrites that receive glutamatergic terminals forming excitatory synapses

Its relevance to neuropathy is most direct in the metabolic neuropathies, particularly diabetic peripheral neuropathy, where impaired glucose metabolism, insulin resistance, and mitochondrial dysfunction all contribute to nerve damage