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Unlike frost-free freezers, which cycle through temperature fluctuations and could further compromise sample integrity, these storage conditions likely minimized additional variability

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bioRxiv2025 Dec 1

Long-term treatment of patients with chronic pelvic pain associated with endometriosis involves repeated courses of medical therapy, surgical therapy, or both

However, in the background of the wild-type enzyme no slight increase in basal activity was observed with these mutations 49 , and as such, we believe that altered oligomerisation should be considered as an aspect of rescue