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Overall, this study did not offer meaningful data to support the clinical efficacy of the approaches studied

It has been prescribed off-label to increase sociability, and to increase sex drive and sexual function

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First, the historical absence of a globally unified definition of rare diseases constrained our study scope to the top ten rare diseases with the highest R&D activity, which may not fully represent the broader spectrum of rare disease research

In fact, some patients have seen improvement in pain levels and mobility after B12 therapy