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Alpha diversity (Observed, Shannon, phylogenetic diversity (PD)) and beta diversity (weighted and unweighted UniFrac) indices were analyzed with rarefied samples (ileum at 21,497, cecum at 34,012, and colon at 7435 reads) in C3H/HeOuJ mice

Consideration: Injections require clinical administration, which provides monitoring and customization opportunities but also demands regular appointments

The peptide's anti-inflammatory and antimicrobial properties provide additional advantages in chronic wound contexts, where persistent inflammation and bacterial colonization frequently impede repair

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Pregnant or breastfeeding women should avoid MOTS-c given the absence of safety data in these populations, as is standard for all investigational peptide therapies