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Thus, when cytosolic NADPH levels rise, the pentose phosphate pathway is downregulated

doi: 10.1038/s41392-020-0116-z [DOI] [PMC free article] [PubMed] [Google Scholar] [58].Samec M, Liskova A, Koklesova L, et al

Severe SARS-CoV-2 infection with high cytokine levels causes T-cell exhaustion characterized by high levels of programmed cell death protein 1 and low numbers of CD4 + and CD8 + cells (Diao et al., 2020