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Investigating the Postprandial Metabolome after Challenge tests to assess metabolic flexibility and Dysregulations Associated with Cardiometabolic diseases

Rice D, Rodriguez-Restrepo A, Mena G, Cata J, Thall P, Milton D, Correa A, Woodard T, Antonoff M, Hofstetter W, Roth J , Sepesi B, Swisher S, Walsh G, Vaporciyan A, Mehran R

FetA produced from hepatocyte by FFAs arrives to adipocytes and acts as an endogenous ligand of TLR4 to promote pro-inflammatory cytokines expression and insulin resistance