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Dendritic Cells and Fibroblasts within TLS Exclusively Expressed the Cystine/Glutamate Transporter, a Key Molecule in Glutathione Synthesis Pathway System x c is the cystine/glutamate transporter that transports extracellular cystine into cells, and its transport activity is regulated by the light chain subunit encoded by Slc7a11

[7] References [edit] 1 2 3 GRCh38: Ensembl release 89: ENSG00000168765 Ensembl, May 2017 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000027890 Ensembl, May 2017 "Human PubMed Reference:"

10.1016/j.jpba.2012.06.026 78 PetersonL

Signal 10 , eaal4186 (2017)

Utilizing the Mac-CF mouse model, we investigated the direct contribution of CF macrophages to lung infection and inflammation