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However, these studies were not followed by large-scale clinical trials which could unambiguously estimate whether thiamine should be given as a treatment for diabetic patients

Extremophiles 15(2):259270 Hu X, Legler PM, Khavrutskii I, Scorpio A, Compton JR, Robertson KL, Friedlander AM, Wallqvist A (2012) Probing the donor and acceptor substrate specificity of the gamma-glutamyl transpeptidase

In the long term, we envision this standardised computation of MISI will allow for easier comparison of MISI across studies and the identification of a cut-off value of MISI indicative of clinical muscle insulin resistance

& Lerner, A

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