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Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons J Neurosci 1998 18 : 1035610365 Erl W, Hansson GK, de Martin R, Draude G, Weber KS, Weber C

Mechanistically, SYVN1 binds to HMGB1, promoting its ubiquitination and degradation and alleviating SCIRI in rats by downregulating HMGB1 and activating the Nrf2/HO-1 pathway