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2025;13:1420 Kurokawa S, Nomura K, Sanada K, Miyaho K, Ishii C, Fukuda S, et al

Eicosanoids and HB-EGF/EGFR in cancer

Conclusion Both the central circadian clock system and the control center of the GH/IGF-1 axis are located in the hypothalamus and related genes/hormones are expressed/released in circadian rhythm, which regulate metabolism through multi-level interactions