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Any way you look at it, this process will take years to work itself out, said Will Woodlee, a partner with the law firm Kleinfeld, Kaplan & Becker LLC, which has represented a wide range of tobacco and e-cigarette companies in their dealings with the FDA

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In sampling multiple electronic cigarette delivery systems, JUUL pods were the only product to demonstrate in vitro cytotoxicity from both nicotine and flavor chemical content, in particular ethyl maltol [28]

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On competing risk analysis, which also considered the risk of death, a significant association persisted between smoking and an increased risk of developing ESKD in all groups except male ex-smokers (Table 2)