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10.3389/fphar.2021.774414 72 ShirwaikarA.ShirwaikarA.RajendranK.PunithaI

Current treatments primarily focus on symptom management, but issues such as drug resistance, side effects, and adverse reactions hinder the long-term effectiveness of these therapies

Substantial variability arises from botanical source, geographic origin, cultivation practices, and extraction methods, yet comprehensive chemical characterization remains absent from many studies