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Mar 2012;55(3):636-643.

Historically, humans consumed these microbes from soil on fresh foods

Rather than blocking the receptor, these auto-Abs are typically stimulatory and cause hyperthyroidism

Isolated MM cells were cultured in Iscoves modified Dulbecos medium supplemented with 20% FBS, insulin, selenium, transferrin, 10 g/ml of gentamycin, 10 ng/ml of interleukin-6, insulin-like growth factor-1 and vascular endothelial growth factor

The pivotal cellular components responsible for desensitization were confirmed by knockdown of those proteins believed to be involved in a regulatory cascade that contributes to receptor desensitization