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Hinckley, A

Garcia-Pavia P, Torres RJ, Rivero M, Ahmed M, Garcia-Puig J, Becker MA

The URE2 gene product of Saccharomyces cerevisiae plays an important role in the cellular response to the nitrogen source and has homology to glutathione s-transferases

Further mechanistic studies have shown that SI can deplete GSH levels, increase ROS levels, promote the release of iron chelated by iron storage proteins, and subsequently promote lipid damage, ultimately leading to ferroptosis in RPECs

Protects Against Mitochondrial Dysfunction: SS-31 preserves mitochondrial function even under stress, making it a potential therapeutic tool in both medicine and performance applications