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In some embodiments, pharmaceutical formulations of the present disclosure may include, lipid nanoparticle that contain disulfiram formulated with D--tocopheryl polyethylene glycol 1000 succinate (vitamin E-TPGS-modified) as described in Baneerjee et al.2019 (Banerjee P, Geng T, Mahanty A, Li T, Zong L, Wang B

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f , HeLa cells expressing the indicated Flag-tagged FL or truncated INTS12 proteins were untreated or treated with 4-NQO and then analyzed as in a

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