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To test this, Leung administered massive doses of B5 (10 to 20 grams per day) to 100 subjects

The results showed that at this pH, mandelic acid alone had an exfoliating effect below 40% of a positive control (10% gluconolactone at pH 4)

Since it appears that some vegetables, particularly Brussels sprouts, may inhibit hepatic FMO3 it is possible that further efficacy may be gained by limiting their intake