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Eli Lilly subsequently attempted to patent this as their discovery but it was rejected in court due to the prior publication by Bloom's group (Bloom email)

159 In another study, oral intake of curcuminoid micelles capsules containing 20.1 mg curcumin, 3.9 mg demethoxycurcumin, and 0.5 mg bisdemethoxycurcumin was shown to be safe, well-tolerated, and enhanced the bioavailability of curcumin in healthy subjects

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For IL-1 antibody blockade, mice were treated with 4 mg kg 1 IL-1 antibody or IgG (Bio X Cell, BE0246, BE0091) before adoptive transfer and the treatment was repeated twice a week