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The glycolysis modulator TIGAR, a fructose-2,6-bisphosphatase (Fru-2,6-BP), also plays a key role in the modulation of metabolism in response to oxidative stress

The expression of TDO2 and IDO1 is upregulated in breast cancer, with high levels of TDO2 closely linked to poor patient prognosis (DAmato et al., 2015

doi: 10.1128/mcb.22.9.2883-2892.2002 111 LaiP

Methods: A cohort of 64 SSNHL, classified into four subtypes (low-frequency, high-frequency, flat and total deafness type), and 53 normal controls (NC) were recruited

This suggests that the future development for humans, especially in underdeveloped countries, is possible after clinical validation with the DLS technique