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Other ALDH2 approaches: Many investigational drugs showed promise in pre-clinical studies, including selective and reversible ALDH2 inhibitors (e.g., ANS-6637) and genetic targeting of liver ALDH2 messenger RNA to locally reduce hepatic ALDH2 expression (305, 306)

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Additionally, a unique cluster of intratumoral CD8 + T cells expressing a putative gene signature of GSH metabolism (GMGS) was associated with clinical response and survival across several human cancers

DOI: 10.1073/pnas.78.8.4767 52

Some areas to consider injecting are at the stomach area, where there is a higher level of fat concentration