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Moreover, we also evaluated the downstream signaling of IGF1R and VEGFR2 in HUVECs cultured in CM of SKOV3shCtrl or shELF3 cells exposed to hypoxia or normoxia, and we did not observe increased expression and secretion of IGF1 under hypoxia, where ELF3 was silenced (Fig 5A)

To characterize the role of piperine as mitochondria respiration regulator, we examined extracellular mitochondria flux with GDP, an UCP1 inhibitor

doi: 10.1016/0021-9150(79)90180-1 207 RastopchinI

Physiol Mol Plant Pathol 42:321336 Bolwell PP, Page A, Pilewska M, Wojtaszek P (2001) Pathogenic infection and the oxidative defences in plant apoplast