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Clin Chem 49(7):11891191 Minkler PE, Stoll MS, Ingalls ST, Kerner J, Hoppel CL (2015) Validated method for the quantification of free and total carnitine, butyrobetaine, and acylcarnitines in biological samples

However, it is not known whether this benefitwould be expected after treatment-associated viral clearance197

recovering and reusing the residues from selective resolution

L-carnitine enhances fatty acid entry into the mitochondria, mitigating their toxic effects in the cytosol, and decreasing the inhibitory effect of acetyl-coenzyme A on the pyruvate dehydrogenase complex caused by intramitochondrial acetate.14 Studies that evaluate L-carnitine supplementation in critically ill patients suggest that it reduces inflammatory biomarkers compared to placebo.15,16 In addition, serum levels of carnitine and its esters in patients with sepsis and septic shock are strong predictors of patient mortality

Moreover, co-encapsulation of synbiotics and L-carnitine as a single microcapsule could be considered as a conceivable delivery system to enhance the stability and efficacy of synbiotics as well as to reduce the cost of the final product